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Protein Cluster CLSK891833: methylated adenine and cytosine restriction protein

Jump to section on this page: Summary Functional Information Phylogenetic Information Sequence Relationships Genes

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Summary
NCBI Protein Clusters accession CLSK891833 (NCBI status: not curated)
Predicted function methylated adenine and cytosine restriction protein
Number of proteins 19
Functional status of component genes: 1 gold (experimental evidence, curated)
1 green (experimental evidence, uncurated)
17 blue (function predicted)
0 black (no functional information)
Related clusters (info)
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Functional Information
NCBI Protein Clusters definition methylated adenine and cytosine restriction protein
EC number N/A
COG functional category Defense mechanisms
Conserved domains (CDD)
  • Mrr: Restriction endonuclease [Defense mechanisms]

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Phylogenetic Information
Phylogenetic domain range Proteobacteria
Taxonomic composition 1 Phyla, 2 Classes, 2 Orders, 5 Genera, 5 species, and 18 Strains
Phylogenetic spread score (info) 2.0

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Sequence Relationships Within This Cluster

The histogram at right summarizes the pairwise distances between all protein sequences in cluster CLSK891833. For each protein sequence, the average pairwise distance to all other protein sequences in the cluster was calculated (a small average distance suggests the sequence lies near the centroid of the cluster, while a large average distance suggests it is an outlier). The histogram shows the number of sequences (y-axis) with an average distance in a given range (x-axis), with bin size specified in figure legend. Average distance information for each gene in this cluster is given below.

We recommend using information from the histogram and tree to help select genes within the cluster to validate experimentally. (Info)

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Genes In This Cluster

Below is a table of genes encoding each protein sequence in this cluster. By default, genes that COMBREX recommends for experimental validation (info) are listed first (these table rows are highlighted), with all remaining genes following in alphabetical order by organism name. Legend for icons:

Functional Status Symbols (info) Footnotes (info)
gold Experimental evidence (curated)

C
Protein Cloned by the Protein Structure Initiative
green Experimental evidence (uncurated)

H
Contains a Pfam domain shared with Human proteins
blue Molecular function predicted

P
Functional Prediction submitted to COMBREX
black No functional information available

R
Recommended for validation by COMBREX

S
Protein Structure available in PDB

U
Protein pUrified by the Protein Structure Initiative