version: 20121102.14

Last Update:
2013.08.26 16:15

Search the COMBREX database (all fields optional; Help)
Enter keyword, gene symbol, or identifier (examples: by keyword, by gene symbol, or by identifier)
Enter species name
Gene functional status (select)
Phenotype association (select) [View list of phenotypes]

Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
Genes with solved structures in PDB
Genes with Pfam domains shared with human proteins
Genes with products purified by PSI
Genes cloned by PSI

What you can do on this site

The COMBREX High Priority Gene List
A list of 100 microbial genes, with predicted functions, most in need of experimental validation. Show List
Successful COMBREX projects
Lists of genes and projects carried out using COMBREX funding. List by gene product. List by investigator.
Prediction and validation status for two model organisms and for all genes in COMBREX

Gold and green sections indicate the number of experimentally validated genes; blue sections indicate the number of unvalidated genes with predicted functions; black sections indicate the number of genes with no predicted functions. See the FAQ for more information.

The good news is that COMBREX has successfully funded many grants to biochemists in its initial phase. The bad news is that our initial allocation of grant money has now been completely utilized. Regrettably, we must suspend funding of further grants until our own funding is renewed. We anticipate this is a temporary situation, as we are sending renewal applications to NIH and continue our strong interest in funding additional COMBREX grants in the near future.

In the meantime, we encourage interested laboratories to send us an email with a short (one or two paragraph) description of your project and this information will be highly helpful in our renewal application. Your full application would be placed at the top of our application stack upon renewal. We also continue to seek submission of predictions from computational prediction teams.

Many thanks for your continued support.