How to find a gene of interest in COMBREX
To find a gene of interest in the COMBREX gene database, enter information about the gene
into the search field within the COMBREX homepage.
In COMBREX, information about a gene is stored within its gene detail page. In order to locate
the appropriate gene detail page, search for it using the search tools on the main page.
COMBREX supports searching for a gene using keywords, Entrez gene id, protein GI,
RefSeq protein accession id, Uniprot id, and gene symbol.
Examples of search terms accepted for a COMBREX query:
Entrez GeneIDs are typically of the form:
RefSeq protein accessions are typically of the form:
Uniprot IDs are typically of the form:
Gene Symbols are typically of the form:
Gene Ontology GO terms are typically of the form:
Enzyme Commission (EC) numbers are typically of the form:
NCBI Protein Cluster accession numbers are typically of the form:
- 2.3.1. (please note: entering only the first two or three digits of an (EC)
number as a search query will produce search results only if a “.” is added
to the end of the terminal number)
and Gene names and keywords can take a variety of forms:
- PRK09601 (NCBI curated)
- CLSK912335 (not yet curated)
In general, the more specific the information used in your search, the easier it is to locate
the specific gene of interest. Therefore, whenever possible, we advise that you search for a
specific gene using its Entrez gene ID or protein GI. If you search using keywords, COMBREX will
in most cases return multiple protein clusters. You must then go through each protein cluster page
until you find the appropriate gene link. Once you have located this link, clicking on it will bring
you to the appropriate gene page.
- aspartate kinase
The advanced search functionality can be used to specify your query and consequently limit your search results,
allowing you to more easily find your gene of interest. Advanced search can be used to specify the organism,
the experimental validation status of the gene, and/or the experimental validation status of the cluster.
Advanced search can also be used to restrict your search to genes with predictions submitted to COMBREX,
genes containing a Pfam domain also found in human genes, genes with structure entries in RCSB Protein Data Bank,
genes with predictions of function submitted to COMBREX, and more.
COMBREX search results yield a list of protein clusters, one of which contains your gene of interest.
If for some reason, your search does not return any results or the results do not contain your gene of interest, please contact us at:
For more information about navigating the Search Results page, the Protein Cluster detail page, and the Gene detail page please see:
Guide to COMBREX website document.