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Gene ygfQ from Escherichia coli str. K-12 substr. MG1655: predicted purine permease

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Summary
Member of NCBI Protein Clusters CLSK870037(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 2847748
UniProtKB accession
RefSeq Protein accession YP_026186.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: ygfQ
  • locus tag: b4464
  • aliases: ECK2880, JW5467, b2884, b2885, ygfR
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: G7503

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Actions You Can Take
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).

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Function Predictions
Source Predicted function(s)
NCBI Protein Cluster Prediction xanthine/uracil/vitamin C permease

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Experimental Validation
Source References Functional description
GSDB Under Review uncharacterized protein ygfQ (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)

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Supporting Functional Information
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0006810 : transport : IEA
  • MF: GO:0005215 : transporter activity : ISS
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • BP: GO:0055085 : transmembrane transport : IEA
  • MF: GO:0005215 : transporter activity : IEA
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0006810 : transport : ISS
  • MF: GO:0000166 : nucleotide binding : IEA
Domain Structure from CDD
  • Xan_ur_permease: Permease family. putative purine permease YbbY; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
AHA_2176 , c3462 , c5056 , CKO_03825 , ECA0783 , EcE24377A_3210 , EcE24377A_4619 , ECH74115_4174 , ECH74115_5568 , EcHS_A3044 , EcHS_A4307 , EcolC_0824 , EcolC_3963 , ECP_2878 , ECP_4293 , ECs3757 , ECs5046 , ECSE_3148 , ECSE_4359 , EcSMS35_3017 , EcSMS35_4527 , Ent638_0269 , ESA_00117 , KP1_0328 , KPK_5204 , NT01EI_3518 , plu4423 , SARI_03407 , SbBS512_E4582 , SeAg_B4528 , SeD_A4663 , SeHA_C4612 , SeSA_A4520 , SNSL254_A4614 , SPAB_05261 , Spro_4431 , SSPA3793 , STY4466 , t4174 , UTI89_C3269 , y0239 , YE3840 , ygfQ (10) , yjcD (29) , YP_3918 , YPA_3642 , YpAngola_A1235 , YPDSF_0236 , YPK_0426 , YPN_3541 , YpsIP31758_0358 , YPTS_3790 , Z4223