Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
Genes with solved structures in PDB
Genes with Pfam domains shared with human proteins
Genes with products purified by PSI
Genes cloned by PSI
close options


Gene Mvan_5269 from Mycobacterium vanbaalenii PYR-1: 2-nitropropane dioxygenase, NPD
Member of NCBI Protein Clusters CLSK872199(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 4644735
UniProtKB accession
RefSeq Protein accession YP_956046.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: Mvan_5269
  • locus tag: Mvan_5269
Organism Mycobacterium vanbaalenii PYR-1 (NCBI TaxID: 350058)
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction 2-nitropropane dioxygenase, NPD
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • BP: GO:0055114 : oxidation reduction : IEA
  • MF: GO:0003824 : catalytic activity : IEA
  • MF: GO:0018580 : 2-nitropropane dioxygenase activity : IEA
  • BP: GO:0008152 : metabolic process : IEA
  • MF: GO:0016702 : oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen : IEA
Domain Structure from CDD
  • NPD: 2-nitropropane dioxygenase. Members of this family catalyse the denitrification of a number of nitroalkanes using either FAD or FMN as a cofactor.
  • NPD_like: 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification .... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database