COMBREX: hpaIIR in Flavobacterium psychrophilum JIP02/86

Home

Share/Save this page

Share this page on...

Grab the link
Here's a link to this page. Just copy and paste.

Or press Ctrl+D (Windows) or Command/Cmd + D (Mac) to bookmark this page

Enter Keyword, gene symbol, or identifier (more options; Help )

	Enter species name
	Gene functional status (select)
	Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX P
Genes with solved structures in PDB S
Genes with Pfam domains shared with human proteins H
Genes with products purified by PSI U
Genes cloned by PSI C
close options

Gene hpaIIR from Flavobacterium psychrophilum JIP02/86: Type II restriction endonuclease HpaII

Jump to section on this page: Summary Actions Predictions Experimental Validation Supporting Info Pathway Information Linked Genes phenotype

Summary

Member of NCBI Protein Clusters	CLSK822567(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID	5300355
UniProtKB accession	A6H1V5
RefSeq Protein accession	YP_001297130.1 (PROVISIONAL)
Gene Symbol(s)	symbol: hpaIIR locus tag: FP2273
Organism	Flavobacterium psychrophilum JIP02/86 (NCBI TaxID: 402612)

Actions You Can Take

	This gene is already gold standard. If you believe there is an additional, validatable function not described here, please contact us.
	Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
	This gene is already gold standard. If you believe there is an additional, validatable function not described here, please contact us.
	Post a comment about this gene to appear on this page (info).

Function Predictions

Source	Predicted function(s)
NCBI Protein Cluster Prediction	type II restriction enzyme HpaII

Experimental Validation

Source	References	Functional description
COMBREX	Under Review	Restriction endonuclease FpsJI, cleaves C/CGG / COMBREX-validated
GSDB	[PMID: 19846593]	FpsJI, Type II restriction enzyme recognizing CCGG (source organism: Flavobacterium psychrophilum; strain specific ID: JIP02/86) / Curator Rich Roberts (record returned: Mar 10 2012)

Supporting Functional Information

Functional Status	Gold (experimental evidence, curated)
EC number	3.1.21.4 (See reaction via BRENDA) (Source: BRENDA) 3.1.21.4 (See reaction via BRENDA) (Source: NCBI RefSeq)
GO terms	MF: GO:0009036 : Type II site-specific deoxyribonuclease activity : IEA MF: GO:0016787 : hydrolase activity : IEA MF: GO:0004519 : endonuclease activity : IEA
Domain Structure from CDD	RE_HpaII: HpaII restriction endonuclease. This family includes the HpaII (recognizes and cleaves C^CGG) restriction endonuclease. See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam	RE_HpaII See domain structure on Pfam Database