Gene HP0347 from Helicobacter pylori 26695: hypothetical protein
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Member of NCBI Protein Clusters
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CLSK872338(See COMBREX Page ) (See NCBI page)
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NCBI Entrez GeneID
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899056
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UniProtKB accession
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RefSeq Protein accession
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NP_207145.1 (PROVISIONAL)
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Gene Symbol(s)
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- symbol: HP0347
- locus tag: HP0347
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Organism
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Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Other Cross References:
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S Structure(s) available in PDB:
C Gene cloned by a participant in the Protein Structure Initiative (PSI):
TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
U Protein purified by a participant in the Protein Structure Initiative (PSI):
TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
- Protein described in EcoCyc:
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Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to
check the list of current predicted functions in the section immediately below beforehand.
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Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally
validated) (info).
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Post a comment about this gene to appear on this page (info).
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Source
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Predicted function(s)
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NCBI Protein Cluster Prediction
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putative ribosomal pseudouridine synthase
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Functional Status
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blue (function predicted, no experimental evidence)
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Source of prediction
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NCBI Protein Clusters info
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BLASTP hits to experimentally validated proteins
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This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
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Share the same Pfam domain composition with the following experimentally validated proteins
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to see the rest 3 genes click here
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GO terms
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MF:
GO:0009982 : pseudouridine synthase activity : IEA
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MF:
GO:0003723 : RNA binding : IEA
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BP:
GO:0001522 : pseudouridine synthesis : IEA
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BP:
GO:0009451 : RNA modification : IEA
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MF:
GO:0016853 : isomerase activity : IEA
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Domain Structure from CDD
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- RluA: Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]
- PseudoU_synth_RluCD_like: PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and TruA. Pseudouridine synthases catalyze the isomerization of specific uridines in a n RNA molecule to pseudouridines (5-ribosyluracil, psi) requiring no cofactors. E. coli RluC for example makes psi955, 2504 and 2580 in 23S RNA. Some psi sites such as psi1917 in 23S RNA made by RluD are universally conserved. Other psi sites occur in a more restricted fashion, for example psi2819 in 21S mitochondrial ribosomal RNA made by S. cerevisiae Pus5p is only found in mitochondrial large subunit rRNAs from some other species and in gram negative bacteria. The E. coli counterpart of this psi residue is psi2580 in 23S rRNA. psi2604in 23S RNA made by RluF has only been detected in E.coli. .... (More)
See domain structure on NCBI Conserved Domain Database
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Domain structure from Pfam
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See domain structure on Pfam Database
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The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page,
as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB).
(Info.)
These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table.
Note: VisANT requires Java. To install the latest version of Java, see www.java.com
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| | HP0348 | single-stranded-DNA-specific exonuclease (recJ) | | | | pyrG | CTP synthase | | | | HP1348 | 1-acyl-glycerol-3-phosphate acyltransferase (plsC) | | | | fmt | methionyl-tRNA formyltransferase | | | | rpmA | 50S ribosomal protein L27 | | | | aspS | aspartyl-tRNA synthetase | | | | rplQ | 50S ribosomal protein L17 | | | | frr | ribosome recycling factor | | | | rnc | ribonuclease III | | | | rplS | 50S ribosomal protein L19 | | | | HP1069 | cell division protein (ftsH) | | | | rplL | 50S ribosomal protein L7/L12 | | | | rpsP | 30S ribosomal protein S16 | | | | HP1245 | single-stranded DNA-binding protein | | | | prfA | peptide chain release factor 1 | | | | HP1497 | peptidyl-tRNA hydrolase | | | | HP0355 | GTP-binding protein LepA | | | | HP1450 | putative inner membrane protein translocase compon | | | | HP0286 | cell division protein (ftsH) | | |
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