Gene mnmA from Helicobacter pylori 26695: tRNA-specific 2-thiouridylase MnmA
Hide
|
Top
|
Member of NCBI Protein Clusters
|
PRK00143(See COMBREX Page ) (See NCBI page)
|
|
NCBI Entrez GeneID
|
899968
|
|
UniProtKB accession
|
|
|
RefSeq Protein accession
|
NP_208127.2 (PROVISIONAL)
|
|
Gene Symbol(s)
|
- symbol: mnmA
- locus tag: HP1335
|
|
Organism
|
Helicobacter pylori 26695 (NCBI TaxID: 85962)
|
|
Other Cross References:
|
S Structure(s) available in PDB:
C Gene cloned by a participant in the Protein Structure Initiative (PSI):
TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
U Protein purified by a participant in the Protein Structure Initiative (PSI):
TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
- Protein described in EcoCyc:
|
Hide
|
Top
|
|
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
|
|
|
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to
check the list of current predicted functions in the section immediately below beforehand.
|
|
|
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally
validated) (info).
|
|
|
Post a comment about this gene to appear on this page (info).
|
Hide
|
Top
|
Functional Status
|
blue (function predicted, no experimental evidence)
|
|
Source of prediction
|
NCBI Protein Clusters info
|
|
EC number
|
2.1.1.61 (See reaction via BRENDA)) (Source: NCBI RefSeq)
|
|
BLASTP hits to experimentally validated proteins
|
other hits with E-value < 1e-05
|
|
Share the same Pfam domain composition with the following experimentally validated proteins
|
to see the rest 2 gene click here
|
|
GO terms
|
-
CC:
GO:0005737 : cytoplasm : IEA
-
MF:
GO:0000166 : nucleotide binding : IEA
-
BP:
GO:0008033 : tRNA processing : IEA
-
MF:
GO:0005524 : ATP binding : IEA
-
BP:
GO:0006400 : tRNA modification : IEA
-
MF:
GO:0000049 : tRNA binding : IEA
-
MF:
GO:0003723 : RNA binding : IEA
-
MF:
GO:0016740 : transferase activity : IEA
|
|
Domain Structure from CDD
|
- tRNA_Me_trans: tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs. This family of enzyme only presents in bacteria and eukaryote. The archaeal counterpart of this enzyme performs same function, but is completely unrelated in sequence..... (More)
- trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase. tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (trmU, asuE, or mnmA) is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine (mnm5s2U34) present in the wobble position of some tRNAs. This enzyme appears not to occur in the Archaea..... (More)
See domain structure on NCBI Conserved Domain Database
|
|
Domain structure from Pfam
|
See domain structure on Pfam Database
|
Hide
|
Top
|
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page,
as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB).
(Info.)
These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table.
Note: VisANT requires Java. To install the latest version of Java, see www.java.com
|
| | 
 | | rpsP | 30S ribosomal protein S16 | | | HP1245 | single-stranded DNA-binding protein | | | aspS | aspartyl-tRNA synthetase | | | rplQ | 50S ribosomal protein L17 | | | rnc | ribonuclease III | | | rplS | 50S ribosomal protein L19 | | | HP1069 | cell division protein (ftsH) | | | prfA | peptide chain release factor 1 | | | HP1497 | peptidyl-tRNA hydrolase | | | rplL | 50S ribosomal protein L7/L12 | | | rpmA | 50S ribosomal protein L27 | | | HP0355 | GTP-binding protein LepA | | | HP1450 | putative inner membrane protein translocase compon | | | HP0286 | cell division protein (ftsH) | | | fmt | methionyl-tRNA formyltransferase | | | frr | ribosome recycling factor | |
|
