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Gene HP0559 from Helicobacter pylori 26695: acyl carrier protein (acpP)

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Summary
Member of NCBI Protein Clusters PRK00982(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900011
UniProtKB accession
RefSeq Protein accession NP_207354.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0559
  • locus tag: HP0559
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)

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Actions You Can Take
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).

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Function Predictions
Source Predicted function(s)
NCBI Protein Cluster Prediction acyl carrier protein
Berkeley Phylogenomics Group GO:0050897 cobalt ion binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0000036 acyl carrier activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0005504 fatty acid binding / (References: 19435885)

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Supporting Functional Information
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green acp from Synechocystis sp. PCC 6803
(%_identity=59.15; E_val=6e-18; BitScore=83.6)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green acpP from Sinorhizobium meliloti 1021

to see the rest 19 genes click here
GO terms
  • CC: GO:0005737 : cytoplasm : IEA
  • BP: GO:0008610 : lipid biosynthetic process : IEA
  • MF: GO:0000036 : acyl carrier activity : IEA
  • MF: GO:0048037 : cofactor binding : IEA
  • MF: GO:0031177 : phosphopantetheine binding : IEA
  • BP: GO:0006633 : fatty acid biosynthetic process : IEA
Domain Structure from CDD
  • PP-binding: Phosphopantetheine attachment site. acyl carrier protein; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database

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Functionally Linked Genes
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
gene neighbourhoods
phylogenetic profile
HP0557acetyl-CoA carboxylase carboxyltransferase subunit
 
  
HP05583-oxoacyl-(acyl carrier protein) synthase II
 
  
fabG3-ketoacyl-(acyl-carrier-protein) reductase
 
 
 
HP1497peptidyl-tRNA hydrolase  
 
aspSaspartyl-tRNA synthetase  
 
rplQ50S ribosomal protein L17  
 
rncribonuclease III  
 
rplS50S ribosomal protein L19  
 
HP1069cell division protein (ftsH)  
 
rplL50S ribosomal protein L7/L12  
 
rpmA50S ribosomal protein L27  
 
HP1450putative inner membrane protein translocase compon  
 
frrribosome recycling factor  
 
HP0355GTP-binding protein LepA  
 
HP1245single-stranded DNA-binding protein  
 
prfApeptide chain release factor 1  
 
rpsP30S ribosomal protein S16  
 
HP0286cell division protein (ftsH)  
 
fmtmethionyl-tRNA formyltransferase  
 

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Phenotype data
Phenotype Description Expression
Class		 Reference(s)
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)