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Gene infA from Helicobacter pylori 26695: translation initiation factor IF-1
Member of NCBI Protein Clusters PRK00276(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900216
UniProtKB accession
RefSeq Protein accession NP_208090.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: infA
  • locus tag: HP1298
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction translation initiation factor IF-1
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0033592 RNA strand annealing activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0003725 double-stranded RNA binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green infA from Bacillus subtilis subsp. subtilis str. 168
(%_identity=65.28; E_val=5e-25; BitScore=107.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green infA from Bacillus subtilis subsp. subtilis str. 168

to see the rest 7 genes click here
GO terms
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0003743 : translation initiation factor activity : IEA
  • BP: GO:0006413 : translational initiation : IEA
  • BP: GO:0006412 : translation : IEA
  • MF: GO:0003723 : RNA binding : IEA
Domain Structure from CDD
  • S1_IF1: S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
HP1299methionine aminopeptidase
secYpreprotein translocase subunit SecY
rpsM30S ribosomal protein S13
rpmJ50S ribosomal protein L36 
Phenotype Description Expression
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)