COMBREX: rpsR in Bacillus subtilis subsp. subtilis str. 168

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Gene rpsR from Bacillus subtilis subsp. subtilis str. 168: 30S ribosomal protein S18

Jump to section on this page: Summary Actions Predictions Experimental Validation Supporting Info Pathway Information Linked Genes phenotype

Summary

Member of NCBI Protein Clusters	PRK00391(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID	937906
UniProtKB accession	P21475
RefSeq Protein accession	NP_391969.2 (PROVISIONAL)
Gene Symbol(s)	symbol: rpsR locus tag: BSU40890
Organism	Bacillus subtilis subsp. subtilis str. 168 (NCBI TaxID: 224308)

Actions You Can Take

	Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
	Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
	Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
	Post a comment about this gene to appear on this page (info).

Function Predictions

Source	Predicted function(s)
NCBI Protein Cluster Prediction	30S ribosomal protein S18

Experimental Validation

Source	References	Functional description
GSDB	Under Review	30S ribosomal protein S18 (source organism: Bacillus subtilis; strain specific ID: NCBI_TaxID=1423)

Supporting Functional Information

Functional Status	Green (experimental evidence, uncurated)
GO terms	CC: GO:0005622 : intracellular : IEA CC: GO:0030529 : ribonucleoprotein complex : IEA BP: GO:0006412 : translation : IEA CC: GO:0005840 : ribosome : IEA MF: GO:0003735 : structural constituent of ribosome : IEA MF: GO:0003723 : RNA binding : IEA MF: GO:0019843 : rRNA binding : IEA
Domain Structure from CDD	Ribosomal_S18: Ribosomal protein S18. 30S ribosomal protein S18; Provisional See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam	Ribosomal_S18 H See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details)	[Download ] GWCH70_3415 , rpsR (19)

Pathway Information

KEGG	bsu03010: Ribosome

Phenotype data

Phenotype	Description	Expression Class	Reference(s)
Candidate essential gene	Identified as essential gene in one or more studies (see references)	Knock out	PMID: 12682299 (candidate essential)