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Gene qseB from Escherichia coli str. K-12 substr. MG1655: quorum sensing DNA-binding response regulator in two-component regulatory system with QseC
Member of NCBI Protein Clusters PRK10336(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 945369
UniProtKB accession
RefSeq Protein accession NP_417497.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: qseB
  • locus tag: b3025
  • aliases: ECK3016, JW2993, preA, ygiX
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: G7575
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Source Predicted function(s)
NCBI Protein Cluster Prediction DNA-binding transcriptional regulator QseB
Source References Functional description
GSDB Under Review transcriptional regulatory protein qseB (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0000160 : two-component signal transduction system (phosphorelay) : IEA
  • MF: GO:0000156 : two-component response regulator activity : IEA
  • BP: GO:0006355 : regulation of transcription, DNA-dependent : IEA
  • BP: GO:0045449 : regulation of transcription : IEA
  • BP: GO:0006350 : transcription : EXP
  • BP: GO:0006350 : transcription : IEA
  • MF: GO:0003677 : DNA binding : IEA
  • MF: GO:0016563 : transcription activator activity : EXP
  • CC: GO:0005737 : cytoplasm : IEA
Domain Structure from CDD
  • trans_reg_C: Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component.... (More)
  • PRK10336: DNA-binding transcriptional regulator QseB; Provisional
  • REC: Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identifie.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
CKO_04414 , EcolC_0672 , ECP_3112 , ECs3907 , ECSE_3306 , Ent638_3429 , qseB (20) , SeAg_B3358 , SeD_A3528 , SeHA_C3427 , SeSA_A3362 , SNSL254_A3433 , SPC_3250 , SSPA2842 , STY3354 , t3098 , ygiX (12)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 phylogenetic profile
gene neighbourhoods
domain fusion
rluB23S rRNA pseudouridylate synthase
qseCquorum sensing sensory histidine kinase in two-com 
rluF23S rRNA U2604 pseudouridine synthase
accCacetyl-CoA carboxylase, biotin carboxylase subunit
murBUDP-N-acetylenolpyruvoylglucosamine reductase, FAD
priAPrimosome factor n' (replication factor Y)
murCUDP-N-acetylmuramate:L-alanine ligase
ddlBD-alanine:D-alanine ligase
clpPproteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP
mrdBcell wall shape-determining protein
accAacetyl-CoA carboxylase, carboxytransferase, alpha
fabF3-oxoacyl-[acyl-carrier-protein] synthase II
radADNA repair protein
ftsWintegral membrane protein involved in stabilizing
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase
rsuA16S rRNA U516 pseudouridine synthase
xseAexonuclease VII, large subunit
ftsItranspeptidase involved in septal peptidoglycan sy
xseBexonuclease VII small subunit
mfdtranscription-repair coupling factor
recNrecombination and repair protein
fabB3-oxoacyl-[acyl-carrier-protein] synthase I
rluE23S rRNA U2457 pseudouridine synthase
recRgap repair protein
polAfused DNA polymerase I 5'->3' polymerase/3'->5' ex
ddlAD-alanine-D-alanine ligase A
mrdAtranspeptidase involved in peptidoglycan synthesis
usgpredicted semialdehyde dehydrogenase
clpXATPase and specificity subunit of ClpX-ClpP ATP-de
fabH3-oxoacyl-[acyl-carrier-protein] synthase III
folK2-amino-4-hydroxy-6-hydroxymethyldihyropteridine p
recGATP-dependent DNA helicase
glmUfused N-acetyl glucosamine-1-phosphate uridyltrans
pspFDNA-binding transcriptional activator  
rtcRsigma 54-dependent transcriptional regulator of rt  
prpRpropionate catabolism operon regulatory protein  
fhlADNA-binding transcriptional activator  
hyfRDNA-binding transcriptional activator, formate sen  
norRAnaerobic nitric oxide reductase DNA-binding trans  
ygeVpredicted DNA-binding transcriptional regulator  
dhaRDNA-binding transcription activator of the dhaKLM