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Gene torR from Escherichia coli str. K-12 substr. MG1655: DNA-binding response regulator in two-component regulatory system with TorS
Member of NCBI Protein Clusters PRK10766(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 946182
UniProtKB accession
RefSeq Protein accession NP_415515.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: torR
  • locus tag: b0995
  • aliases: ECK0986, JW0980
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB: 1ZGZ
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG12615
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction DNA-binding transcriptional regulator TorR
Source References Functional description
GSDB Under Review TorCAD operon transcriptional regulatory protein torR (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0000160 : two-component signal transduction system (phosphorelay) : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0000156 : two-component response regulator activity : IEA
  • BP: GO:0006355 : regulation of transcription, DNA-dependent : IEA
  • BP: GO:0045449 : regulation of transcription : IEA
  • BP: GO:0006350 : transcription : IEA
  • MF: GO:0005515 : protein binding : IPI
  • MF: GO:0003677 : DNA binding : IEA
Domain Structure from CDD
  • trans_reg_C: Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component.... (More)
  • REC: Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identifie.... (More)
  • PRK10766: DNA-binding transcriptional regulator TorR; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
EcolC_2600 , ECP_0993 , ECs1150 , ECSE_1057 , NT01EI_0301 , SSPA3430 , torR (30)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 phylogenetic profile
domain fusion
murBUDP-N-acetylenolpyruvoylglucosamine reductase, FAD
 
 
accAacetyl-CoA carboxylase, carboxytransferase, alpha
 
 
polAfused DNA polymerase I 5'->3' polymerase/3'->5' ex
 
 
ddlAD-alanine-D-alanine ligase A
 
 
usgpredicted semialdehyde dehydrogenase
 
 
clpXATPase and specificity subunit of ClpX-ClpP ATP-de
 
 
mrdBcell wall shape-determining protein
 
 
folK2-amino-4-hydroxy-6-hydroxymethyldihyropteridine p
 
 
xseBexonuclease VII small subunit
 
 
murCUDP-N-acetylmuramate:L-alanine ligase
 
 
clpPproteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP
 
 
radADNA repair protein
 
 
recRgap repair protein
 
 
rluB23S rRNA pseudouridylate synthase
 
 
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-mes
 
 
ftsWintegral membrane protein involved in stabilizing
 
 
mfdtranscription-repair coupling factor
 
 
rluF23S rRNA U2604 pseudouridine synthase
 
 
recNrecombination and repair protein
 
 
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase
 
 
mrdAtranspeptidase involved in peptidoglycan synthesis
 
 
fabB3-oxoacyl-[acyl-carrier-protein] synthase I
 
 
accCacetyl-CoA carboxylase, biotin carboxylase subunit
 
 
ftsItranspeptidase involved in septal peptidoglycan sy
 
 
rsuA16S rRNA U516 pseudouridine synthase
 
 
fabH3-oxoacyl-[acyl-carrier-protein] synthase III
 
 
priAPrimosome factor n' (replication factor Y)
 
 
ddlBD-alanine:D-alanine ligase
 
 
recGATP-dependent DNA helicase
 
 
glmUfused N-acetyl glucosamine-1-phosphate uridyltrans
 
 
rluE23S rRNA U2457 pseudouridine synthase
 
 
xseAexonuclease VII, large subunit
 
 
fabF3-oxoacyl-[acyl-carrier-protein] synthase II
 
 
yneFpredicted diguanylate cyclase 
 
ydeHdiguanylate cyclase, required for pgaD induction 
 
dhaRDNA-binding transcription activator of the dhaKLM  
 
yfiNpredicted diguanylate cyclase 
 
dosCdiguanylate cyclase 
 
yedQpredicted diguanylate cyclase 
 
yeaJpredicted diguanylate cyclase 
 
yliFpredicted diguanylate cyclase 
 
rtcRsigma 54-dependent transcriptional regulator of rt 
 
ygeVpredicted DNA-binding transcriptional regulator 
 
hyfRDNA-binding transcriptional activator, formate sen 
 
yeaIpredicted diguanylate cyclase 
 
adrAdiguanylate cyclase for cellulose, biofilm, motili 
 
dosPoxygen sensor, c-di-GMP phosphodiesterase, heme-re 
 
yhjKpredicted diguanylate cyclase 
 
yeaPdiguanylate cyclase 
 
ydaMdiguanylate cyclase, csgD regulator 
 
gmrcyclic-di-GMP phosphodiesterase; csgD regulator; m 
 
yegEpredicted diguanylate cyclase, GGDEF domain signal 
 
ycdTdiguanylate cyclase 
 
prpRpropionate catabolism operon regulatory protein 
 
fhlADNA-binding transcriptional activator 
 
pspFDNA-binding transcriptional activator 
 
norRAnaerobic nitric oxide reductase DNA-binding trans 
 
Phenotype Description Expression
Class
Reference(s)
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 13129938
(candidate essential)
PMID: 17700540
(not essential)
PMID: 20029369
(not essential)