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Gene yphF from Escherichia coli str. K-12 substr. MG1655: predicted sugar transporter subunit: periplasmic-binding component of ABC superfamily
Member of NCBI Protein Clusters CLSK880430(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947020
UniProtKB accession
RefSeq Protein accession NP_417043.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: yphF
  • locus tag: b2548
  • aliases: ECK2545, JW2532
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: G7342
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Source Predicted function(s)
NCBI Protein Cluster Prediction putative sugar transporter subunit: periplasmic-binding component of ABC superfamily
Source References Functional description
GSDB Under Review ABC transporter periplasmic-binding protein yphF (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0042597 : periplasmic space : IEA
Domain Structure from CDD
  • RbsB: ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]
  • PBP1_ABC_sugar_binding_like: Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein .... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
EcE24377A_2833 , ECH74115_3781 , EcHS_A2700 , EcolC_1129 , ECP_2549 , ECs3414 , ECSE_2835 , EcSMS35_2701 , yphF (16)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
domain fusion
yphEfused predicted sugar transporter subunits of ABC
rbsCD-ribose transporter subunit 
lsrCAutoinducer 2 import system permease protein 
araHfused L-arabinose transporter subunits of ABC supe 
lsrDautoinducer 2 import system permease protein 
xylHD-xylose ABC transporter permease subunit 
mglCmethyl-galactoside transporter subunit 
alsCD-allose transporter subunit 
ytfTpredicted sugar transporter subunit: membrane comp 
yjfFpredicted sugar transporter subunit: membrane comp 
yphDpredicted sugar transporter subunit: membrane comp