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Gene rsmD from Escherichia coli str. K-12 substr. MG1655: 16S rRNA m(2)G966 methyltransferase, SAM-dependent
Member of NCBI Protein Clusters PRK10909(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947977
UniProtKB accession
RefSeq Protein accession NP_417922.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: rsmD
  • locus tag: b3465
  • aliases: ECK3449, JW3430, yhhF
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB: 2FPO
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG10343
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction 16S rRNA m(2)G966-methyltransferase
Source References Functional description
GSDB
[PMID: 17189261]
Ribosomal RNA small subunit methyltransferase D (source organism: Escherichia coli (strain K12).; strain specific ID: )
Functional Status greenGreen (experimental evidence, uncurated)
EC number 2.1.1.52 (See reaction via BRENDA)) (Source: BRENDA)
GO terms
  • BP: GO:0006364 : rRNA processing : IEA
  • MF: GO:0008990 : rRNA (guanine-N2-)-methyltransferase activity : IDA
  • MF: GO:0008168 : methyltransferase activity : IEA
  • BP: GO:0070475 : rRNA base methylation : IMP
  • MF: GO:0003676 : nucleic acid binding : IEA
  • MF: GO:0005515 : protein binding : IPI
  • MF: GO:0008990 : rRNA (guanine-N2-)-methyltransferase activity : IEA
  • MF: GO:0016740 : transferase activity : IEA
  • BP: GO:0032259 : methylation : IEA
Domain Structure from CDD
  • AdoMet_MTases: S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
rsmD (49) , yhhF (2)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 phylogenetic profile
murBUDP-N-acetylenolpyruvoylglucosamine reductase, FAD
 
clpXATPase and specificity subunit of ClpX-ClpP ATP-de
 
rpsA30S ribosomal subunit protein S1
 
murCUDP-N-acetylmuramate:L-alanine ligase
 
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-mes
 
clpPproteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP
 
rluB23S rRNA pseudouridylate synthase
 
mrdBcell wall shape-determining protein
 
mrdAtranspeptidase involved in peptidoglycan synthesis
 
mfdtranscription-repair coupling factor
 
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase
 
ftsWintegral membrane protein involved in stabilizing
 
ftsItranspeptidase involved in septal peptidoglycan sy
 
rsuA16S rRNA U516 pseudouridine synthase
 
priAPrimosome factor n' (replication factor Y)
 
rluF23S rRNA U2604 pseudouridine synthase
 
rluE23S rRNA U2457 pseudouridine synthase