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Gene basR from Escherichia coli str. K-12 substr. MG1655: DNA-binding response regulator in two-component regulatory system with BasS
Member of NCBI Protein Clusters PRK10643(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 948631
UniProtKB accession
RefSeq Protein accession NP_418537.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: basR
  • locus tag: b4113
  • aliases: ECK4106, JW4074, pmrA
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11615
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction DNA-binding transcriptional regulator BasR
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green basR from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
(%_identity=90.54; E_val=1e-116; BitScore=413.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green phoP from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

to see the rest 51 genes click here
GO terms
  • BP: GO:0000160 : two-component signal transduction system (phosphorelay) : IEA
  • BP: GO:0045449 : regulation of transcription : IEA
  • BP: GO:0046677 : response to antibiotic : IEA
  • BP: GO:0010041 : response to iron(III) ion : IMP
  • MF: GO:0003677 : DNA binding : IEA
  • MF: GO:0016563 : transcription activator activity : IMP
  • BP: GO:0006350 : transcription : IEA
  • BP: GO:0010041 : response to iron(III) ion : IEP
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0000156 : two-component response regulator activity : IEA
  • BP: GO:0006355 : regulation of transcription, DNA-dependent : IEA
  • BP: GO:0000160 : two-component signal transduction system (phosphorelay) : IDA
  • BP: GO:0006355 : regulation of transcription, DNA-dependent : IMP
Domain Structure from CDD
  • trans_reg_C: Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component.... (More)
  • REC: Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identifie.... (More)
  • PRK10643: DNA-binding transcriptional regulator BasR; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 gene neighbourhoods
phylogenetic profile
basSsensory histidine kinase in two-component regulato
 
 
mfdtranscription-repair coupling factor 
 
recNrecombination and repair protein 
 
fabB3-oxoacyl-[acyl-carrier-protein] synthase I 
 
rluE23S rRNA U2457 pseudouridine synthase 
 
recRgap repair protein 
 
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-mes 
 
mrdBcell wall shape-determining protein 
 
mrdAtranspeptidase involved in peptidoglycan synthesis 
 
fabH3-oxoacyl-[acyl-carrier-protein] synthase III 
 
ftsWintegral membrane protein involved in stabilizing  
 
recGATP-dependent DNA helicase 
 
glmUfused N-acetyl glucosamine-1-phosphate uridyltrans 
 
rluF23S rRNA U2604 pseudouridine synthase 
 
accCacetyl-CoA carboxylase, biotin carboxylase subunit 
 
murBUDP-N-acetylenolpyruvoylglucosamine reductase, FAD 
 
priAPrimosome factor n' (replication factor Y) 
 
ddlBD-alanine:D-alanine ligase 
 
murCUDP-N-acetylmuramate:L-alanine ligase 
 
clpPproteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP 
 
accAacetyl-CoA carboxylase, carboxytransferase, alpha  
 
fabF3-oxoacyl-[acyl-carrier-protein] synthase II 
 
radADNA repair protein 
 
polAfused DNA polymerase I 5'->3' polymerase/3'->5' ex 
 
folK2-amino-4-hydroxy-6-hydroxymethyldihyropteridine p 
 
ddlAD-alanine-D-alanine ligase A 
 
rluB23S rRNA pseudouridylate synthase 
 
clpXATPase and specificity subunit of ClpX-ClpP ATP-de 
 
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase 
 
usgpredicted semialdehyde dehydrogenase 
 
rsuA16S rRNA U516 pseudouridine synthase 
 
xseAexonuclease VII, large subunit 
 
ftsItranspeptidase involved in septal peptidoglycan sy 
 
xseBexonuclease VII small subunit