Phenotypes
Summary
| Phenotype | Description | #Genes | Functional status | Source |
|---|---|---|---|---|
| Antibiotic resistance class Aac2I | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class Aac2Ic | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 9 | 0 0 9 0 | ARDB |
| Antibiotic resistance class Aac2Id | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Aac3Ia | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class Aac3IIa | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class Aac3VI | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class Aac6Ib | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 15 | 0 0 15 0 | ARDB |
| Antibiotic resistance class Aac6Ie | Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. | 12 | 0 0 12 0 | ARDB |
| Antibiotic resistance class aad9Ib | Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. | 19 | 0 0 19 0 | ARDB |
| Antibiotic resistance class AadD | Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. | 8 | 0 1 7 0 | ARDB |
| Antibiotic resistance class AcrA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 49 | 0 1 48 0 | ARDB |
| Antibiotic resistance class AcrB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 84 | 0 1 83 0 | ARDB |
| Antibiotic resistance class AdeA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class AdeB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class AdeC | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class AmrA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 10 | 0 0 10 0 | ARDB |
| Antibiotic resistance class AmrB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 17 | 0 0 17 0 | ARDB |
| Antibiotic resistance class Ant2Ia | Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class Ant3Ia | Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. | 27 | 0 0 27 0 | ARDB |
| Antibiotic resistance class Ant6Ia | Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Aph33Ia | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Aph33Ib | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 55 | 0 0 55 0 | ARDB |
| Antibiotic resistance class Aph3Ia | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 29 | 0 0 29 0 | ARDB |
| Antibiotic resistance class Aph3Ib | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class Aph3Ic | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Aph3IIIa | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 5 | 0 1 4 0 | ARDB |
| Antibiotic resistance class Aph6Ia | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Aph6Ic | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class Aph6Id | Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. | 49 | 0 0 49 0 | ARDB |
| Antibiotic resistance class arnA | Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 27 | 0 1 26 0 | ARDB |
| Antibiotic resistance class BacA | Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate. | 354 | 0 1 353 0 | ARDB |
| Antibiotic resistance class bcr | 49 | 0 1 48 0 | ARDB | |
| Antibiotic resistance class BcrA | ABC transporter system, bacitracin efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL1_ceps | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL1_cmy2 | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 13 | 0 0 13 0 | ARDB |
| Antibiotic resistance class BL1_ec | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 31 | 0 1 30 0 | ARDB |
| Antibiotic resistance class BL1_fox | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL1_mox | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL1_och | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL1_pao | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class BL1_pse | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL1_sm | Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL2_kpc | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class BL2_len | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL2_veb | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL2a_1 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 17 | 0 0 17 0 | ARDB |
| Antibiotic resistance class BL2a_III | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 17 | 0 1 16 0 | ARDB |
| Antibiotic resistance class BL2a_III2 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL2a_pc | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 15 | 0 0 15 0 | ARDB |
| Antibiotic resistance class BL2b_rob | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class BL2b_tem | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class BL2b_tem1 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 34 | 0 0 34 0 | ARDB |
| Antibiotic resistance class BL2b_tem2 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class BL2be_ctxm | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 7 | 0 0 7 0 | ARDB |
| Antibiotic resistance class BL2be_shv2 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 8 | 0 0 8 0 | ARDB |
| Antibiotic resistance class BL2c_pse1 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL2d_lcr1 | Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL2d_oxa1 | Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 1 0 0 | ARDB |
| Antibiotic resistance class BL2d_oxa2 | Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class BL2d_oxa9 | Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class BL2e_cepa | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL2e_y56 | Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class BL3_cphA | Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL3_imp | Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL3_l | Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class BL3_shw | Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Ble | Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage | 8 | 0 0 8 0 | ARDB |
| Antibiotic resistance class Blt | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 1 | 0 1 0 0 | ARDB |
| Antibiotic resistance class Bmr | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 1 | 0 1 0 0 | ARDB |
| Antibiotic resistance class catA1 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 14 | 0 0 14 0 | ARDB |
| Antibiotic resistance class catA13 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class catA15 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class catA2 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 10 | 0 0 10 0 | ARDB |
| Antibiotic resistance class catA3 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class catA4 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class catA7 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class catA8 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class catA9 | Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. | 7 | 0 0 7 0 | ARDB |
| Antibiotic resistance class catB1 | Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class catB2 | Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class catB3 | Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class catB4 | Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. | 2 | 0 1 1 0 | ARDB |
| Antibiotic resistance class catB5 | Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class CeoA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 18 | 0 2 16 0 | ARDB |
| Antibiotic resistance class CeoB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 30 | 0 2 28 0 | ARDB |
| Antibiotic resistance class cml_e1 | Major facilitator superfamily transporter, chloramphenicol efflux pump. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class cml_e3 | Major facilitator superfamily transporter, chloramphenicol efflux pump. | 11 | 0 0 11 0 | ARDB |
| Antibiotic resistance class cml_e5 | Major facilitator superfamily transporter, chloramphenicol efflux pump. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class cml_e8 | Major facilitator superfamily transporter, chloramphenicol efflux pump. | 7 | 0 0 7 0 | ARDB |
| Antibiotic resistance class dfrA1 | Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. | 9 | 0 0 9 0 | ARDB |
| Antibiotic resistance class dfrA12 | Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class dfrA14 | Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class dfrA17 | Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class dfrA19 | Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class EmeA | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class emrd | Multidrug resistance efflux pump. | 50 | 0 1 49 0 | ARDB |
| Antibiotic resistance class EmrE | Multidrug resistance efflux pump. | 23 | 0 1 22 0 | ARDB |
| Antibiotic resistance class ErmA | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 19 | 0 0 19 0 | ARDB |
| Antibiotic resistance class ErmB | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 19 | 0 0 19 0 | ARDB |
| Antibiotic resistance class ErmC | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 13 | 0 0 12 1 | ARDB |
| Antibiotic resistance class ErmE | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class ErmO | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class ErmT | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class ErmX | rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class FosB | Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin | 45 | 1 0 44 0 | ARDB |
| Antibiotic resistance class FosX | Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin | 6 | 0 1 5 0 | ARDB |
| Antibiotic resistance class fusB | Involved in the resistance (detoxification) of the fungal toxin fusaric acid. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class fusH | Esterase enzyme inactivating fusidic acid | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class KsgA | Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance. | 58 | 0 1 57 0 | ARDB |
| Antibiotic resistance class LmrB | ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump. | 2 | 0 1 1 0 | ARDB |
| Antibiotic resistance class lmrp | 2 | 0 0 2 0 | ARDB | |
| Antibiotic resistance class LnuA | Lincosamide nucleotidyltransferase. | 13 | 0 0 13 0 | ARDB |
| Antibiotic resistance class lsa | ABC efflux family that is resistant to MLS antibiotics | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class MacA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system. | 50 | 0 1 49 0 | ARDB |
| Antibiotic resistance class MacB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system. | 49 | 0 1 48 0 | ARDB |
| Antibiotic resistance class mdfa | 49 | 0 1 48 0 | ARDB | |
| Antibiotic resistance class mdr | 3 | 0 1 2 0 | ARDB | |
| Antibiotic resistance class mdtE | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 27 | 0 1 26 0 | ARDB |
| Antibiotic resistance class mdtF | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 28 | 0 1 27 0 | ARDB |
| Antibiotic resistance class mdtG | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 46 | 0 0 46 0 | ARDB |
| Antibiotic resistance class MdtH | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 51 | 0 1 50 0 | ARDB |
| Antibiotic resistance class MdtK | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 51 | 0 1 50 0 | ARDB |
| Antibiotic resistance class MdtL | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 31 | 0 1 30 0 | ARDB |
| Antibiotic resistance class MdtM | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 33 | 0 1 32 0 | ARDB |
| Antibiotic resistance class MdtN | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 29 | 0 0 29 0 | ARDB |
| Antibiotic resistance class MdtO | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 27 | 0 0 27 0 | ARDB |
| Antibiotic resistance class MdtP | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 28 | 0 1 27 0 | ARDB |
| Antibiotic resistance class mecA | Penicillin binding protein, which has a low affinity for beta-lactams and catalyze a penicillin-insensitive transpeptidation. | 12 | 0 0 12 0 | ARDB |
| Antibiotic resistance class MecR1 | Methicillin-resistance regulatory protein for mecA | 11 | 0 0 11 0 | ARDB |
| Antibiotic resistance class MefA | Major facilitator superfamily transporter, Macrolide-Lincosamide-Streptogramin B efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class MepA | Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump. | 17 | 0 1 16 0 | ARDB |
| Antibiotic resistance class MexA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 1 3 0 | ARDB |
| Antibiotic resistance class MexB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 6 | 0 1 5 0 | ARDB |
| Antibiotic resistance class MexC | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class MexD | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 9 | 0 0 9 0 | ARDB |
| Antibiotic resistance class MexE | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class MexF | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 16 | 0 0 16 0 | ARDB |
| Antibiotic resistance class mexh | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class mexi | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class mexw | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 13 | 0 0 13 0 | ARDB |
| Antibiotic resistance class MexX | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class MexY | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class MfpA | Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. | 9 | 0 0 9 0 | ARDB |
| Antibiotic resistance class MphA | Macrolide phosphotransferase | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class MphC | Macrolide phosphotransferase | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class MsrA | ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class nora | 19 | 0 0 19 0 | ARDB | |
| Antibiotic resistance class norM | Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump. | 4 | 0 1 3 0 | ARDB |
| Antibiotic resistance class OpcM | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 10 | 0 0 10 0 | ARDB |
| Antibiotic resistance class opmd | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class OprA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class OprJ | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class OprM | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 1 3 0 | ARDB |
| Antibiotic resistance class OprN | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 4 | 0 0 4 0 | ARDB |
| Antibiotic resistance class pbp1a | The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) | 4 | 0 1 3 0 | ARDB |
| Antibiotic resistance class pbp1b | The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class pbp2 | The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) | 15 | 0 0 15 0 | ARDB |
| Antibiotic resistance class pbp2b | The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class pbp2x | The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) | 11 | 0 2 9 0 | ARDB |
| Antibiotic resistance class PmrA | Major facilitator superfamily transporter. Multidrug resistance efflux pump. | 11 | 0 0 11 0 | ARDB |
| Antibiotic resistance class Qac | Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class QacA | Multidrug efflux pump from bacterial pathogen staphylococcus aureus. Including QacA and QacB, both of which confer resistance to various toxic organic cations but differ in that QacB mediates lower levels of resistance to divalent cations. They differed by seven nucleotide subsititutions. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class QnrA | Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class QnrB | Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class QnrS | Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class RosA | Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter. | 11 | 0 0 11 0 | ARDB |
| Antibiotic resistance class RosB | Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter. | 13 | 0 0 13 0 | ARDB |
| Antibiotic resistance class SmeA | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class SmeB | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class SmeC | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class SmeD | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class SmeE | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class SmeF | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class str | Streptomycin resistance protein. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class Sul1 | Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide. | 55 | 0 0 55 0 | ARDB |
| Antibiotic resistance class Sul2 | Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide. | 54 | 0 0 54 0 | ARDB |
| Antibiotic resistance class Sul3 | Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class tcmA | Major facilitator superfamily transporter. Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class tet | Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class tet33 | Major facilitator superfamily transporter, tetracycline efflux pump. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class tet34 | Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class tet38 | Major facilitator superfamily transporter, tetracycline efflux pump. | 14 | 0 0 14 0 | ARDB |
| Antibiotic resistance class tetA | Major facilitator superfamily transporter, tetracycline efflux pump. | 30 | 0 0 30 0 | ARDB |
| Antibiotic resistance class tetB | Major facilitator superfamily transporter, tetracycline efflux pump. | 20 | 0 1 19 0 | ARDB |
| Antibiotic resistance class tetC | Major facilitator superfamily transporter, tetracycline efflux pump. | 10 | 0 0 10 0 | ARDB |
| Antibiotic resistance class tetD | Major facilitator superfamily transporter, tetracycline efflux pump. | 7 | 0 0 7 0 | ARDB |
| Antibiotic resistance class tetG | Major facilitator superfamily transporter, tetracycline efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class tetH | Major facilitator superfamily transporter, tetracycline efflux pump. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class tetJ | Major facilitator superfamily transporter, tetracycline efflux pump. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class tetK | Major facilitator superfamily transporter, tetracycline efflux pump. | 10 | 0 0 10 0 | ARDB |
| Antibiotic resistance class tetL | Major facilitator superfamily transporter, tetracycline efflux pump. | 8 | 0 1 7 0 | ARDB |
| Antibiotic resistance class tetM | Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. | 14 | 0 0 14 0 | ARDB |
| Antibiotic resistance class tetO | Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. | 6 | 0 0 6 0 | ARDB |
| Antibiotic resistance class tetPA | Major facilitator superfamily transporter, tetracycline efflux pump. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class tetPB | Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. | 2 | 0 1 1 0 | ARDB |
| Antibiotic resistance class tetS | Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class tetV | Major facilitator superfamily transporter, tetracycline efflux pump. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class tetW | Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class tetZ | Major facilitator superfamily transporter, tetracycline efflux pump. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class TmrB | Mechanism unknown. | 1 | 0 1 0 0 | ARDB |
| Antibiotic resistance class TolC | Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. | 52 | 0 1 51 0 | ARDB |
| Antibiotic resistance class VanA | VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class VanB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 2 | 0 1 1 0 | ARDB |
| Antibiotic resistance class VanHA | VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class VanHB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 2 | 0 1 1 0 | ARDB |
| Antibiotic resistance class VanRA | VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 7 | 0 0 7 0 | ARDB |
| Antibiotic resistance class VanRB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 3 | 0 0 3 0 | ARDB |
| Antibiotic resistance class VanSA | VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 7 | 0 0 7 0 | ARDB |
| Antibiotic resistance class VanSB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class VanWB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class VanXA | VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class VanXB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class VanYA | VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class VanYB | VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. | 2 | 0 0 2 0 | ARDB |
| Antibiotic resistance class VanZ | VanZ confers low-level VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class VatB | Virginiamycin A acetyltransferase, which can inactivate the target drug. | 5 | 0 0 5 0 | ARDB |
| Antibiotic resistance class VgaA | ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump. | 1 | 0 0 1 0 | ARDB |
| Antibiotic resistance class VgbA | Streptogramin B Lyase, which can deactivate the target drug by hydrolysis. | 1 | 0 0 0 1 | ARDB |
| Antibiotic resistance class YkkC | Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins. | 2 | 0 1 1 0 | ARDB |
| Antibiotic resistance class YkkD | Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins. | 2 | 0 1 1 0 | ARDB |
| Ciprofloxacin sensitivity | Knockout confers increased sensitivity to ciprofloxacin | 55 | 0 37 18 0 | Prof. Jeffrey Miller |
| Enoxacin sensitivity | Knockout confers increased sensitivity to enoxacin | 47 | 0 31 16 0 | Prof. Jeffrey Miller |
| Nitrofurantoin sensitivity | Knockout confers increased sensitivity to nitrofurantoin | 136 | 1 92 43 0 | Prof. Jeffrey Miller |
| Metronidazole sensitivity | Knockout confers increased sensitivity to metronidazole | 82 | 0 63 19 0 | Prof. Jeffrey Miller |
| Sulfamethoxazole sensitivity | Knockout confers increased sensitivity to sulfamethoxazole | 65 | 1 47 17 0 | Prof. Jeffrey Miller |
| Rifampicin sensitivity | Knockout confers increased sensitivity to rifampicin | 87 | 2 64 21 0 | Prof. Jeffrey Miller |
| Gentamicin sensitivity | Knockout confers increased sensitivity to gentamicin | 51 | 1 36 14 0 | Prof. Jeffrey Miller |
| Tobramycin sensitivity | Knockout confers increased sensitivity to tobramycin | 60 | 1 43 16 0 | Prof. Jeffrey Miller |
| Neomycin sensitivity | Knockout confers increased sensitivity to neomycin | 67 | 1 47 19 0 | Prof. Jeffrey Miller |
| Streptomycin sensitivity | Knockout confers increased sensitivity to streptomycin | 29 | 1 22 6 0 | Prof. Jeffrey Miller |
| Spectinomycin sensitivity | Knockout confers increased sensitivity to spectinomycin | 36 | 1 30 5 0 | Prof. Jeffrey Miller |
| Tetracycline sensitivity | Knockout confers increased sensitivity to tetracycline | 56 | 0 37 19 0 | Prof. Jeffrey Miller |
| Vancomycin sensitivity | Knockout confers increased sensitivity to vancomycin | 56 | 0 39 17 0 | Prof. Jeffrey Miller |
| Ampicillin sensitivity | Knockout confers increased sensitivity to ampicillin | 85 | 1 54 30 0 | Prof. Jeffrey Miller |
| Cephradine sensitivity | Knockout confers increased sensitivity to cephradine | 70 | 1 48 21 0 | Prof. Jeffrey Miller |
| Cefoxitin sensitivity | Knockout confers increased sensitivity to cefoxitin | 56 | 1 35 20 0 | Prof. Jeffrey Miller |
| Azetreonam sensitivity | Knockout confers increased sensitivity to azetreonam | 41 | 1 23 17 0 | Prof. Jeffrey Miller |
| Colistin sensitivity | Knockout confers increased sensitivity to colistin | 52 | 1 36 15 0 | Prof. Jeffrey Miller |
| Chloramphenicol sensitivity | Knockout confers increased sensitivity to chloramphenicol | 46 | 1 31 14 0 | Prof. Jeffrey Miller |
| Erythromycin sensitivity | Knockout confers increased sensitivity to erythromycin | 52 | 1 39 12 0 | Prof. Jeffrey Miller |
| Fusidic Acid sensitivity | Knockout confers increased sensitivity to fusidic | 43 | 0 33 10 0 | Prof. Jeffrey Miller |
| Triclosan sensitivity | Knockout confers increased sensitivity to triclosan | 75 | 1 53 21 0 | Prof. Jeffrey Miller |
| Candidate essential gene | Identified as essential gene in one or more studies (see references) | 2467 | 13 623 1675 156 |